陈金中
男,1964年出生,博士,副教授。1980-1985年就读中南大学湘雅医学院,获得临床医学学学士,1998-2001年就读于华中科技大学同济医学院,获遗传学硕士学位。2001-2004年在复旦大学遗传学研究所攻读博士学位。2004年到复旦大学基因治疗课题组工作,2006年任职副教授,2007年开始负责课题组日常研究工作。
求学经历
1985湖南医学院,医学学士;2001年同济医科大学,遗传学硕士;2004年复旦大学,ph D。
研究方向
基因治疗,功能基因组
获奖情况
代表性论文和专著:
1. Wang Lu, Yao Jihua, Chen Li, Chen Jinzhong, Xue Jinglun, Jia William Expression and possible functional roles of cytochromes P450 2J1 (zfCyp 2J1) in 斑马fish BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 352 (4): 850-855 JAN 26 2007
2. Chen JZ, Ji CN, Xu GL, et al. DAXX interacts with phage Phi C31 integrase and inhibits recombination NUCLEIC ACIDS RESEARCH 34 (21): 6298-6304 DEC 2006
3. Zhang JY, Chen JZ, Liu LF, et al. Different gene expression profiles of AD293 and HEK293 cell lines that show contrasting susceptibility to apoptosis induced by overexpression of Bim L ACTA BIOCHIMICA POLONICA 53 (3): 525-530 2006
4. Zhang, Jiayi, Liu, Lingfeng, Zhang, Xiaomeng, Jin, Feng, Chen, Jinzhong, Ji, Chaoneng, Gu, Shaohua, Xie, Yi, Mao, Yumin Cloning and characterization of a novel human prefoldin and SPEC domain protein gene (PFD6L) from the fetal brain BIOCHEMICAL GENETICS 44 (1-2): 66-71 FEB 2006
5. Zheng NC, Huang BM, Xu J, Huang SS, Chen JZ, Hu XC, Ying K, Yu XB. Enzymatic and physico-chemical characteristics of recombinant cMDH and mMDH of Clonorchis sinensis PARASITOLOGY RESEARCH 99 (2): 174-180 JUL 2006
6. Feng DM, Chen JZ, Yue YB, et al. A 16 bp Rep binding element is sufficient for mediating Rep-dependent integration into AAVS1 JOURNAL OF MOLECULAR 生物学 358 (1): 38-45 APR 21 2006
7. Li JX, Ji CN, Chen JZ, et al. Identification and characterization of a novel Cut family cDNA that encodes human copper transporter protein CutC BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 337 (1): 179-183 NOV 11 2005
8. Chen JZ, Huang SD, Ji CN, et al. Identification, expression pattern, and subcellular location of human RIP isoforms 脱氧核糖核酸 AND CELL 生物学 24 (7): 464-469 JUL 2005
9. Zheng NC, Xu J, Wu ZD, Chen JZ, Hu XC, Song LX, Yang G, Ji CN, Chen SY, Gu SH, Ying K, Yu XB. Clonorchis sinensis: molecular cloning and functional expression of novel cytosolic malate dehydrogenase EXPERIMENTAL PARASITOLOGY 109 (4): 220-227 APR 2005
10. Zhang JY, Dai JL, Zhao EP, Lin Y, Zeng L, Chen JZ, Zheng H, Wang Y, Li X, Ying K, Xie Y, Mao YM cDNA cloning, gene organization and expression analysis of human 磷酸烯醇丙酮酸tidyFAL自动步枪ginine deiminase type VI ACTA BIOCHIMICA POLONICA 51 (4): 1051-1058 2004
11. Chen JZ, Ji CN, Gu SH, et al. Over-expression of Bim alpha 3, a novel isoform of human Bim, result in cell apoptosis INTERNATIONAL JOURNAL OF BIOCHEMISTRY \u0026 CELL 生物学 36 (8): 1554-1561 AUG 2004
12. Zhao EP, Li Y, Fu XP, Zhang JY, Zeng HW, Zeng L, Lin Y, Chen JZ, Yin G, Qian J, Ying K, Xie Y, Zhao RC, Mao YM Cloning and expression of human GTDC1 gene (glycosyltransferase-like domain containing 1) from human fetal library 脱氧核糖核酸 AND CELL 生物学 23 (3): 183-187 MAR 2004
13. Li JX, Ji CN, Yang QS, Chen JZ, Gu SH, Ying K, Xie Y, Mao YM Cloning and characterization of a novel human TGF-beta activated kinase-like gene BIOCHEMICAL GENETICS 42 (3-4): 129-137 APR 2004
14. Liu H, Chen JZ, Gu SH, et al. Assignment of human sprouty 4 gene to chromosome segment 5q32 similar to 33 and analysis of its pattern of expression JOURNAL OF GENETICS 82 (1-2): 23-26 APR-AUG 2003
15. Zhao EP, Li JS, Xie Y, Jin W, Zhang Z, Chen JZ, Zeng L, Yin G, Qian J, Wu H, Ying K, Zhao RCH, Mao YM Cloning and identification of a novel human RNPC3 gene that encodes a protein with two RRM domains and is expressed in the cell nucleus BIOCHEMICAL GENETICS 41 (9-10): 315-323 OCT 2003
16. Jin G, Wang S, Hu XG, Jing ZP, Chen JZ, Ying K, Xie Y, Mao YM Characterization of the tissue-specific expression of the S100P gene which encodes an 悠久之翼hand ca(clo)2+-binding protein MOLECULAR 生物学 REPORTS 30 (4): 243-248 DEC 2003
17. Zhao EP, Li Y, Fu XP, Zeng L, Zeng HW, Jin W, Chen JZ, Yin G, Qian J, Ying K, Xie Y, Zhao RCH, Mao YM Cloning and characterization of human synaptotagmin 10 gene 脱氧核糖核酸 SEQUENCE 14 (5): 393-398 SEP 2003
18. Gu SH, Chen JZ, Ying K, et al. Cloning and identification of a novel cDNA which encodes a putative protein with a DnaJ domain and a thioredoxin active motif, human macrothioredoxin BIOCHEMICAL GENETICS 41 (7-8): 245-253 AUG 2003
19. Chen JZ, Ji CN, Gu SH, et al Isolation and identification of a novel cDNA that encodes human yrdC protein JOURNAL OF HUMAN GENETICS 48 (4): 164-169 2003
20. Wang S, Chen JZ, Zhang Z, et al. Cloning, expression and genomic structure of a novel human GNB2L1 gene, which encodes a receptor of activated proTEIN kinase C (RACK) MOLECULAR 生物学 REPORTS 30 (1): 53-60 MAR 2003
21. Ji CN, Chen JZ, Xie Y, et al. A novel cDNA encodes a putative hRALY-like protein, hRALYL MOLECULAR BIOLOGY REPORTS 30 (1): 61-67 MAR 2003
22. Meng XF, Zhang C, Chen JZ, et al. Cloning and identification of a novel cDNA coding thioredoxin-related transmembrane protein 2 BIOCHEMICAL GENETICS 41 (3-4): 99-106 APR 2003
23. Wang S, Zhang Z, Ying K, Chen JZ, Meng XF, Yang QS, Xie Y, Mao YM Cloning, expression, and genomic structure of a novel human Rap2 interacting gene (RPIP9) BIOCHEMICAL GENETICS 41 (1-2): 13-25 FEB 2003
24. Chen JZ, Wang S, Tang R, et al. Cloning and identification of a cDNA that encodes a novel human protein with thrombospondin type I repeat domain, hPWTSR CULAR 生物学 REPORTS 29 (3): 287-292 SEP 2002
25. Chen JZ, Yang QS, Wang S, et al. Cloning and expression of a novel 视网膜母细胞瘤 binding protein cDNA, RBBP10 BIOCHEMICAL GENETICS 40 (7-8): 273-282 奥地利AUG5.56毫米轻机枪 2002
26. Yang QS, Ying K, Yuan HL, Chen JZ, Meng XF, Wang Z, Xie Y, Mao YM Cloning and expression of a novel human galectin cDNA, predominantly expressed in placenta BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1574 (3): 407-411 APR 12 2002
27. Yang QS, Xia F, Gu SH, Yuan HL, Chen JZ, Yang QS, Ying K, Xie Y, Mao YM Cloning and expression pattern of a spermatogenesis-related gene, BEX1, mapped to chromosome Xq22 BIOCHEMICAL GENETICS 40 (1-2): 1-12 FEB 2002
28. Wang S, Chen JZ, Zhang Z, et al. Cloning, characterization, and expression of calcyphosine 2, a novel human gene encoding an EF-hand ca(clo)2+-binding protein BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 291 (2): 414-420 FEB 22 2002