赵子龙

赵子龙，男，湖南大学湖南文理学院化学化工学院副教授，曾参与荧光探针性能调控与生物成像应用基础研究项目，并担任主要完成人。2021年11月3日，他荣获2020年度国家自然科学奖二等奖。

人物经历

教育经历

工作经历

2010.01-2011.01，任佛罗里达大学，博士后。

2011.11-2013.11，任湖南大学，博士后。

2013.12-2016.12，任湖南大学生物学院，副研究员。

曾参与荧光探针性能调控与生物成像应用基础研究项目，担任主要完成人。

主要成就

科研成就

研究领域

化学生物学、纳米生物学

科研成果

1、国家自然科学基金青年基金，特异性识别胰导管腺癌核酸适配体的筛选及其诊治应用的初步研究（21405041），2015.01-2017.12，25万元，主持

2、国家自然科学基金国家重大科研仪器研制项目，基于核酸适配体识别的肿瘤细胞新型标志物高效筛选仪的研制子课题（61527806），2016.01-2020.12，214万元，主持

论文

. Zilong Zhao, Li Xu, Xiaoli Shi, Weihong Tan, Xiaohong Fang*, Dihua Shangguan*, Recognition of Subtype Non-Small Cell Lung Cancer by 脱氧核糖核酸 Aptamers Selected from Living Cells, Analyst, 2009, 134(9): 1808-1814.

. Zilong Zhao, Hongmin Meng, Nannan Wang, Micheal J Donovan, Ting Fu, Mingxu You, Zhuo Chen, Xiaobing Zhang*, Weihong Tan*, A Controlled-Release Nanocarrier with Extracellular pH Value Driven Tumor Targeting and Translocation for Drug Delivery, Angew. Chem. Int. Ed., 2013, 52(29): 7487-7491.

. Nannan Wang#, Zilong Zhao#, Yifan Lv, Huanhuan Fan, Huarong Bai, Hongmin Meng, Yuqian Long, Ting Fu, Xiaobing Zhang, Weihong Tan*, Gold Nanorod-Photosensitizer Conjugate with Extracellular pH-Driven Tumor Targeting Ability for Photothermal/Photodynamic Therapy, Nano Research, 2014,7(9): 1291-1301.

. Zilong Zhao#, Huanhuan Fan#, Gaofeng Zhou, Huarong Bai, Hao Liang, Ruowen Wang, Xiaobing Zhang, Weihong Tan*, Activatable 荧光/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet-Aptamer Nanoprobe, J. Am. Chem. Soc., 2014, 136(32): 11220-11223. （高被引论文）

. Xiaoqiu Wu#, Zilong Zhao#, Huarong Bai, Ting Fu, Chao Yang, Xiaoxiao Hu, Qiaoling Liu, Carole Champanhac, I-Ting Teng, Mao Ye*, Weihong Tan*, 脱氧核糖核酸 Aptamer Selected against Pancreatic Ductal Adenocarcinoma for in vivo Imaging and Clinical Tissue Recognition, Theranostics, 2015, 5(9): 985-994.

. Jun Hu#, Zilong Zhao#, Qiaoling Liu, Mao Ye, Bingqiang Hu, Jing Wang, Weihong Tan*, Study of the 函数 of G-Rich Aptamers Selected for Lung Adenocarcinoma, Chem. Asian J., 2015, 10(7): 1519-1525.

. Huanhuan Fan#, Zilong Zhao#, Guobei Yan, Xiaobing Zhang, Chao Yang, Hongmin Meng, Zhuo Chen, Hui Liu, Weihong Tan*, A Smart DNAzyme–MnO2 Nanosystem for Efficient Gene Silencing, Angew. Chem. Int. Ed., 2015, 54(16): 4801-4805.

. Xia Li#, Bo Zhou#, Zilong Zhao#, Zixi Hu, Sufang Zhou, Nuo Yang, Yong Huang, Zhenghua Zhang, Jing Su, Dan Lan, Xue Qin, Jinyu Meng, Duo Zheng, Jian He,Xianing Huang, Jing Zhao, Zhiyong Zhang, Weihong Tan*, Xiaoling Lu*, Yongxiang Zhao*, A Smart Detection System Based on Specific Magnetic and Rolling Cycle Amplification Signal-amplified Dual-Aptamers to Accurately Monitor Minimal Residual Diseases in Patients with T-ALL, J. Biomed. Nanotechnol., 2016, 12(12): 2151-2160.

. Yongbo Peng#, Zilong Zhao#, Teng Liu#, Guojian Xie, Cheng Jin, Tanggang Deng, Yang Sun, Xiong Li, Xiaoxiao Hu, Xiaobing Zhang, Mao Ye, Weihong Tan*, A Multi-Mitochondrial Anticancer Agent that Selectively Kills Cancer Cells and Overcomes Drug Resistance, ChemMedChem, 2017, 12(3): 250-256.

. Hailan Kuai#, Zilong Zhao#, Liuting Mo, Hui Liu, Xiaoxiao Hu, Ting Fu, Xiaobing Zhang, Weihong Tan*, Circular Bivalent Aptamers Enable in vivo Stability and Recognition, J. Am. Chem. Soc., 2017, 139(27): 9128-9131.

. Wenting Jia, Caiping Ren*, Lei Wang, Bin Zhu, Wei Jia, Menghui Gao, Fei Zeng, Liang Zeng, Xiaomeng Xia, Xiaobing Zhang, Ting Fu, Shasha Li, Can Du, Xingjun Jiang, Yuxiang Chen, Weihong Tan, Zilong Zhao*, Weidong Liu*, CD109 Is Identified as a Potential Nasopharyngeal Carcinoma Biomarker Using Aptamer Selected by 细胞SELEX, 2016, Oncotarget, 2016, 7(34): 55328-55342.

. Xuan Yu, Liang Gong, Jing Zhang, Zilong Zhao*, Xiaobing Zhang*, Weihong Tan*, Nanocarrier Based on the Assembly of Protein and Antisense Oligonucleotide to Combat Multidrug Resistance in Tumor Cells, Science China 化学, 2017, 60(10): 1318-1323.

. Yongbo Peng#, ZilongZhao#*, TengLiu#, XiongLi, Xiaoxiao Hu, Xiaoping Wei, XiaobingZhang, WeihongTan*, Smart Human-Serum-Albumin-As2O3 Nanodrug with Self-amplified Folate Receptor-Targeting Ability for Chronic Myeloid 白血病 Treatment, Angew. Chem. Int. edc, 2017, 56(36): 10845-10849.

. Ying Jiang, Xiaoshu pan, Jin Chang, Weijia Niu, Weijia Hou, Hailan Kuai, Zilong Zhao*, Ji Liu, Ming Wang*, Weihong Tan*, Supramolecularly Engineered Circular Bivalent Aptamer for Enhanced Functional Protein Delivery, J. Am. Chem. Soc., 2018, DOI: 10.1021/jacs.8b03442.

人物荣誉

2021年11月3日，2020年度国家科学技术奖励大会在北京人民大会堂隆重举行，担任主要完成人的荧光探针性能调控与生物成像应用基础研究项目荣获2020年度国家自然科学奖二等奖。

参考资料

最全！2020年度国家科学技术奖励名单.科学网.2021-11-03