1. 简单百科
  2. 潘建平

潘建平

潘建平,浙江大学医学部病原生物学系副主任、免疫学教授、博士研究生导师,中国免疫学会理事,浙江省免疫学会感染免疫专业委员会主任委员,浙江省抗癌协会肿瘤生物治疗委员会委员兼秘书,“International Journal of Cancer”、“Vaccine”等期刊审稿人。

研究方向

主要研究方向:肿瘤免疫学,黏膜抗感染免疫的细胞和分子机制

主要项目

在研科主要研项目:不同亚群PP-DC在B细胞向肠黏膜归巢和IgA产生中的作用及其机制(国家自然科学基金,30872325)

发表论文

发表的主要论文:

⒈ Lu J,Zheng MH,Yan J,Chen YP,pan J. Effects of vasoactive intestinal peptide on phenotypic and functional maturation of dendritic cells. Inter Immunopharmacol 2008; 8:1449-1454.

⒉ Pan J,Jin P,Yan J,Kabelitz D. Anti-angiogenic active immunotherapy: a new approach to cancer treatment. Cancer Immunol Immunother 2008; 57:1105-1114.

⒊ Weng Y,Sun J,Wu Q,pan J. Regulatory effects of vasoactive intestinal peptide on the migration of mature dendritic cells. J Neuroimmunol 2007; 182: 48-54.

⒋ Shao P,Zhao LH,Chen Z,Pan J. Regulation on maturation and function of dendritic cells by Astragalus mongholicus 多糖 Inter Immunopharmacol 2006; 6: 1161-1166.

pan J,Heiser A,Maret M,Steinmann J,Kabelitz D. Enhanced anti-metastatic effect of fetal liver kinase 1 and interferon-gamma fusion gene-modified dendritic cell vaccination. Gene Ther 2005; 12:742-750.

pan J,Zhang M,Wang J,Wang Q,Xia D,Sun W,Zhang L,Yu H,Cao X. Intratumoral injection of interferon-gamma gene-modified dendritic cells elicits potent antitumor effects: effective induction of tumor-specific CD8+ CTL response. J Cancer Res Clin Oncol 2005; 131:468-478.

pan J,Zhang M,Wang J,Wang Q,Xia D,Sun W,Zhang L,Yu H,Liu Y,Cao X. Interferon-gamma is an autocrine mediator for dendritic cell maturation. Immunol Lett. 2004; 94 : 141-151.

pan J,Ju DW,Wang Q,Zhang M,Xia D,Zhang L,Yu H,Cao X. Dexamethosone inhibits the antigen presentation of dendritic cells in MHC class Ⅱ pathway. Immunol Lett 2001; 76 ⑶: 153-161.

⒐ Zhang LH,pan JP,Yao HP,et al. Intrasplenic transplantation of IL-18 gene-modified hepatocytes: an effective approach to reverse hepatic fibrosis in schistosomiasis through induction of dominant Th1 response. Gene Ther 2001; 8: 1333-1342.

⒑ Sun W,Wang Q,Zhang L,pan J,Zhang M,Lu G,Yao H,Wang J,Cao X. TGF-beta ⑴ gene modified immature dendritic cells exhibit enhanced tolerogenicity but induce allograft fibrosis in vivo J 摩尔 Med. 2002; 80 ⑻: 514-23.

⒒ Xia DJ,Zhang WP,Zheng S,Wang J,pan JP,Wang Q,Zhang LH,Hamada H,Cao X. Lymphotactin cotransfection enhances the therapeutic efficacy of dendritic cells genetically modified with melanoma antigen gp100. Gene Ther 2002; 9 ⑼: 592-601.

⒓ Xia D,Zheng S,Zhang W,He L,Wang Q,pan J,Zhang L,Wang J,Cao X. Effective induction of therapeutic antitumor immunity by dendritic cells coexpressing interleukin-18 and tumor antigen. J 摩尔 Med. 2003; 81 ⑼: 585-96.

⒔ Wang Q,Yu H,Ju DW,He L,pan JP,Xia D,Zhang L,Cao X. Intratumoral IL-18 gene transfer improves therapeutic efficacy of antibody-targeted superantigen in established murine melanoma. Gene Ther 2001; 8 ⑺: 542-550.

⒕ Wang Q,Yu H,Zhang LH,Ju DW,pan JP,Xia DJ,He L,Wang J,Cao X. Vaccination with IL-18 gene-modified,superantigen-coated tumor cells elicits potent antitumor immune response. J Cancer Res Clin Oncol 2001; 127 ⑿: 718-726.

⒖ Wang Q,Yu H,Zhang LH,Ju DW,pan JP,Xia DJ,He L,Wang J,Cao X. Adenovirus-mediated intratumoral lymphotactin gene transfer potentiates the antibody-targeted superantigen therapy of cancer. J 摩尔 Med 2002; 80 ⑼: 585-594.

获奖情况

⒈张立煌、姚航平、冷建杭、李敏伟、陈红、潘建平、孙文。细胞因子基因修饰肝细胞经脾移植治疗肝纤维化和肝癌的实验研究。浙江省科学技术奖三等奖。2003年12月。

⒉严杰、毛亚菲、孙爱华、罗冬娇、潘建平、陈学军等。内置LTB幽门螺杆菌UreB-HpaA两价口服基因工程疫苗的实验研究。浙江省科学技术奖二等奖。2007年09月。

主编和参编的著作和教材:

⒈潘建平,邵传森主编。《医学免疫学》浙江大学出版社,2006年8月第一版。

⒉潘建平。第八章 抗原和抗原提呈,第九章 免疫应答,第十章 免疫耐受,第十一章 免疫调节。张丽芳,张立煌主编。《医学免疫学与微生物学》。北京市人民卫生出版社,2007年2月第一版。65-104.

⒊祝文娴,潘建平。肺的免疫功能。周汉良,陈季强主编。呼吸药理学与治疗学。第一版。北京:人民卫生出版社,1999年。175-206

参考资料