秦峰
秦峰,女,博士,研究员,博士生导师。1975年10月出生于湖北省武汉市,1998年和2001年在华中农业大学获学士和硕士学位,2004年在清华大学获博士学位。2004年至2010年在日本国际农林水产业研究中心从事博士后研究工作。2010年入选中国科学院“百人计划”,任中国科学院植物研究所研究员。近年来在Plant Cell、Plant Journal、Plant Physiology、PNAS上发表论文数十篇。
人物经历
1994年9月至1998年7月,秦峰就读于华中农业大学,获学士。1998年9月至2001年7月,秦峰在华中农业大学攻读,获硕士学位。2001年9月至2004年7月,秦峰于清华大学就读,获博士学位。2004年至2010年,秦峰在日本国际农林水产业研究中心进行博士后研究工作。2010年,其入选中国科学院“百人计划”。秦峰在《Plant Cell》《Plant Journal》《Plant Physiology》《美国国家科学院院刊》上发表论文数十篇。
研究工作
通过对抗旱性的全基因组关联分析,发掘和克隆玉米中重要的抗旱候选基因,利用分子生物学的研究手段和方法,阐明基因在植物体内的功能。同时分析玉米不同转录因子基因家族(AP2/EREBP、bZIP、NAC)中的各成员对抗旱性的贡献,确定玉米中在抵抗干旱胁中最重要的转录因子。研究旨在鉴定和克隆玉米中重要的抗旱性基因,并运用克隆到的基因或分子标记改良玉米抗旱性。
2. RING类型蛋白泛素化E3 连接酶在植物抗逆和发育中的作用
蛋白泛素化是真核生物蛋白质重要的转录后修饰方式之一,参与调节细胞周期进程、细胞增生与分化,以及信号传导等多种生理过程。植物中很多类型的转录因子也受到泛素化的修饰,如DRIP1\u00262泛素化E3连接酶能特异识别受干旱和高盐诱导的转录因子DREB2A,并通过控制其在细胞内的稳定性,参与植物水分胁迫的信号传递。我们希望(1)进一步发现特异与DRIP1\u00262相互作用的蛋白;(2)DRIP1\u00262在植物抗水分胁迫和生长发育中的功能;(3)玉蜀黍属中含RING结构域泛素化E3连接酶在抵抗水分胁迫中德的功能。
科研项目
“玉米抗旱基因的克隆与功能分析”,中国科学院知识创新工程项目,(项目编号:KSCX2-YW-N-097)(2011.01-2013.12)
“拟南芥泛素化E3连接酶DRIP1及其互作蛋白在响应水分胁迫应答中的分子机理”自然科学基金面上项目,(项目编号:31171163)(2012.1-2015.12
专利
刘强,秦峰,陈受宜 玉米DREB类转录因子及其编码基因与应用:中国,02125373.2. 2002-08-20.
主要作品
代表性论文
1.Yang Z#,Cao Y#,Shi Y#,Qin F*,Jiang,C*,Yang S*.Genetic and molecular exploration of maize environmental stress resilience:Toward sustainable agriculture.Moleclar Plant.2023,16:1-22.
2.Tian T#,Wang S#,Yang S,Yang Z,Liu S,Wang Y,Gao H,Zhang S,Yang X,Jiang C,Qin F*.Genome assembly and genetic dissection of a prominent drought-resistant maize germplasm.Nature Genetics.2023,55:496-506.
3.Yang Z,Qin F*.The battle of crops against drought:Genetic dissection and improvement.Joural of Integrative Plant Biology.2023,65:496-525.
4.Gao H,Cui J,Liu S,Wang S,Lian Y,Bai Y,Zhu T,Wu H,Wang Y,Yang S,Li X,Zhuang J,Chen L,Gong Z,Qin F*.Natural variations of ZmSRO1d modulate the trade-off between drought resistance and yield by affecting ZmRBOHC-mediated stomatal ROS production in maize.Molecular Plant.2022,15:1558-157.
5.Liu SX,Qin F*.Genetic dissection of maize drought tolerance for trait improvement,Molecular Breeding,2021,41(8):1-13.
6.Liu B,Zhang B,Yang Z,Liu Y,Yang S,Shi Y,Jiang C,Qin F*.Manipulating ZmEXPA4 expression ameliorates the drought-induced prolonged anthesis and silking interval in maize.Plant Cell,2021,33:2058-2071.
7.Liu S#,Li C#,Wang H,Wang S,Yang S,Liu X,Yan J,Li B,Beatty M,Zastrow-Hayes G,Song S*,Qin F*.Mapping regulatory variants controlling gene expression in drought response and tolerance in maize.Genome Biology,2020,21:163.
8.Zhang X,Mi Y,Mao H,Liu S,Chen L,Qin F*.Genetic variation in ZmTIP1 contributes to root hair elongation and drought tolerance in maize.Plant Biotechnology Journal,2020,18:1271-1283.
9.Jiang LG,Li B,Liu SX,Wang HW,Li CP,Song SH,Beatty M,Zastrow-Hayes G,Yang XH,Qin F*,He Y*.Characterization of proteome variation during modern maize breeding.Molecular \u0026 Cellular Proteomics,2019,18:263-276.
10.Wang H,Qin F*.Genome wide association study reveals natural variations contributing to drought resistance in crops.Frontiers in Plant Science,2017,8:1110.
11.Wang X#,Wang H#,Liu S,Ferjani A,Li J,Yan J,Yang X*,Qin F*.Genetic variation in ZmVPP1 contributes to drought tolerance in maize seedlings.Nature Genetics,2016,48:1233-1241.
12.Ding S#,Zhang B#,Qin F*.Arabidopsis RZFP34/CHYR1,a ubiquitin E3 ligase,regulates stomatal movement and drought tolerance via SnRK2.6-mediated phosphorylation.Plant Cell,2015,27:3228-3244.
13.Mao H,Wang H,Liu S,Li Z,Yang X,Yan J,Li J,Tran LP,Qin F*.A transposable element in a NAC gene is associated with drought tolerance in maize seedlings.Nature Communications,2015,6:8326.
14.Liu SX,Wang XL,Wang HW,Xin HB,Yang XH,Yan JB,Li JS,Tran LSP,Shinozaki K,Yamaguchi-Shinozaki K,Qin F*.Genome-Wide Analysis of ZmDREB Genes and Their Association with Natural Variation in Drought Tolerance at Seedling Stage of Zea mays L.PLoS Genetics,2013,9:e1003790.
15.Ma Y,Qin F*,Tran LS*.Contribution of Genomics to Gene Discovery in Plant Abiotic Stress Responses.Molecular Plant,2012,5:1176-1178.
16.Qin F,Sakuma Y,Tran LS ,Maruyama K,Kidokoro S,Fujita Y,Fujita M,Umezawa T,Sawano Y,Miyazono K,Tanokura M,Shinozaki K,and Yamaguchi-Shinozaki K.Arabidopsis DREB2A-Interacting Proteins 函数 as RING E3 Ligases and Negatively Regulate Plant Drought 应力Responsive Gene Expression.Plant Cell,2008,20:1693-1707.
17.Qin F,Kodaira K,Maruyama K,Mizoi J,Tran L-S P,Fujita Y,Morimoto K,Shinozaki K,Yamaguchi-Shinozaki K.SPINDLY,a Negative Regulator of GA Signaling,Is Involved in the Plant Abiotic Stress Response.Plant Physiology,2011,157:1900-1913.
18.Qin F,Yamaguchi-Shinozaki K and Shinozaki K.Achievements and Challenges in Understanding Plant Abiotic Stress Response and Tolerance.Plant \u0026 Cell Physiology,2011,52:1569-1582.
19.Qin F,Kakimoto M,Sakuma Y,Maruyama K,Osakabe Y,Tran L.P.,Shinozaki K and Yamaguchi-Shinozaki K.Regulation and Functional Analysis of ZmDREB2A in Response to Drought and Heat Stresses in Zea mays L.Plant Journal,2007,50:54-69.
20.Qin F,Li J S,Li X H and Corke H.AFLP and RFLP linkage map in coix.Genetic Resources and Crop Evolution,2005,52:209-214.
21.Qin F,Sakuma Y,Li J,Liu Q,Li YQ,Shinozaki K and Yamaguchi-Shinozaki K.Cloning and functional analysis of a novel DREB1/CBF transcription factor involved in cold-responsive gene expression in Zea mays L.Plant \u0026 Cell Physiology,2004,45:1042-1052.
22.Jiang YX#,Qin F#,Ma XY,Li YQ,Bai CL and Fang XH.Measuring specific interaction of transcription factor ZmDREB1A with its 脱氧核糖核酸 responsive element at the molecular level.Nucleic Acids Research,2004,32:e101.
23.Qin F,Li J,Zhang GY,Zhao Jun,Chen SY and Liu Q.Isolation and characterization of a DRE-binding transcription factor from maize.Acta Botanica Sinica,2003,45:331-339.
24.Qin F,Jiang YX,Ma XY,Chen F,Fang XH,Bai CL and Li YQ.Specific Interaction of Transcription Factor and 脱氧核糖核酸 Element Investigated by Atomic Force Microscopy.Chinese Science Bulletin,2004,49:1376-1380.
参考资料:
人物荣誉
2014年5月9日,杜邦向全球10位青年学者颁发了2014年度青年教授奖。中科院植物研究所秦峰研究员获奖,并成为本年度唯一获得该奖项的大陆学者。
参考资料
秦峰.中国科学院大学.2024-07-19
秦峰.中国农业大学生物学院.2024-07-19