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翟万银

翟万银,男,博士,副研究员,2002年6月毕业于华东师范大学生命科学院生物化学与分子生物学专业,获硕士学位。

个人信息

翟万银,副研。

简历

2011年6月毕业于中国科学院上海微系统与信息技术研究所微电子学与固体电子专业,获博士学位。2002年7月进入中国科学院上海硅酸盐研究所生物材料与组织工程研究中心。主要研究方向(1)生物材料的生物相容性研究和(2)心血管组织工程研究。主持完成上海市自然基金项目“用猪主动脉瓣及人骨髓干细胞构建人心脏瓣膜病”,国家863项目“新型纳米药物载体靶向控释技术及其细胞生物学效应研究”子课题;作为主要完成人完成了国家自然基金项目“复合天然交联剂对动物心脏瓣膜交联作用的研究”、“天然交联剂原花青素对动物心脏瓣膜交联作用的研究”,目前承担国家自然基金面上项目“多酚对瓣膜弹性蛋白的交联及其在原位组织工程瓣膜支架制备中的应用研究”。

发表论文

1.Zhai W, Chang J, Lin K, Wang J, Zhao Q, Sun X. Crosslinking of decellularized porcine heart 维尔福集团 by procyanidins. Biomaterials

2. Zhai W, Chang J, Lu X. Procyanidins crosslinked heart valve matrix: Anti-calcification effect. Journal of Biomedical Materials Research Part B: Appl Biomater

3. Zhai W, Lu X, Chang J, Zhou Y, Zhang H. 槲皮素 crosslinked porcine heart 维尔福集团 matrix: mechanical property, stability, anti-calcification and cytocompatibility. Acta Biomaterialia

4. LüX, Zhai W (co-First author), Zhou Y, Zhou Y, Zhang H, Chang J. Crosslinking effect of Nordihydroguaiaretic acid (NDGA) on decellularized heart valve scaffold for tissue engineering, J. Mater Sci:Mater Med

5. Zhai W, Jia C, Zhao H, Xu Y. Procyanidins inhibit tumor angiogenesis by crosslinking extracellular matrix. Chin J Cancer Res

6. 翟万银,吴蕾,贾春平,邵建波,徐元森 肿瘤微血管芯片的制备及其在通透性检测方面的应用. 功能材料与器件学报, 2011,.

7. 翟万银,周双雯,贾春萍,徐元森. 藤黄酸抗肿瘤细胞生物学机制研究进展. 细胞生物学学报

8. Zhai W, Jia C, Lou X, Jin Q, Zhao J, Xu Y. Enhanced antitumor activity of Irinotecan combined with gambogic acid on NSCLC. 21st IUBMB and 12st FAOBMB International Congress of Biochemistry and Molecular 生物学, August 2-7, 2009, Shanghai, China. Abstract

9. Zhai W, Lu H, Chen L, Lin X, Huang Y, Dai K, Naoki K, Chen G, Chang J. Akermanite, a silicate bioceramic, stimulates in vitro and in vivo angiogenesis European Cell and Material Journal, Under review.

10. Zhai W, He C, Wu L, Zhou Y, Guo L, Chen Y, Chen H, Chang J. Degradation of hollow mesoporous silica nanoparticles (HMSN) in human umbilical vein endothelial cells. NAOmedicine: Nanotechnology 生物学 Medicine, Under review.

11. Zhai W, Lu H, Chen L, Lin X, Huang Y, Dai K, Naoki K, Chen G, Chang J. Implications from comparative study on containing ceramics and β-TCP: the key role of Si in in vitro cell proliferation, osteo-differentiation and angiogenesis. Biomaterials, Submitted.

12. Zhai W, Chang J. Procyanidins-crosslinked porcine heart valve matrix: mechanical characteristics, stability and biocompatibility. Oral

13. Zhai W, Chang J. Crosslinking-decellularized valvular ECM for bioprostheses using procyanidins. Chinese Biomaterials Congress, Chengdu, Oral

14. 何常亮, 翟万银(共通讯作者),张红霞, 常江,张红峰,郭利民,陈航榕. 中空介孔硅球对血管内皮细胞的细胞毒性。华东师范大学学报(自然科学板)

15. Xie Y, Zhai W, Chen L, Chang J, Zheng X and Ding C. Preparation and in vitro evaluation of plasma-sprayed Mg2SiO4 coating on titanium alloy. Acta Biomaterialia

16. Zhang M, Zhai W, Lin K, pan H, Lu W, Chang J. Synthesis, in-vitro 羟基磷灰石 forming ability, and cytocompatibility of silicate powders. Journal of Biomedical Materials Research Part B (JBMR:B), Applied Biomaterials, Inpress.

17. Wu C, Chang J, Zhai W, Ni S, Wang J. Porous akermanite scaffolds for bone tissue engineering: Preparation, characterization, and in vitro studies. Journal of Biomedical Materials Research Part B: Applied Biomaterials

18. Zhao L, Chang J and Zhai W. Preparation and HL-7702 cell functionality of titania/chitosan composite scaffolds. J Mater Sci: Mater Med

19. Zhao W, Chang J, Zhai W. Self-setting properties and in vitro bioactivity of Ca3SiO5/CaSO4 1/2H2o composite cement. Journal of Biomedical Materials Research Part A

20. Wu C, Chang J, Zhai W and Ni S. A novel bioactive porous bredigite (Ca7MgSi4O16) scaffold with biomimetic apatite layer for bone tissue engineering.Journal of Materials Science: Materials in Medicine

21. Zhao L, Chang J, Zhai W. Experimental research of preparation and characterization of chito苯乙烯-丙烯腈共聚物/TiO2 composite films. Journal of Tissue Engineering and Reconstructive Sugery,

22. Du RL, Chang J, Ni SY, Zhai W, Wang JY, Characterization and in vitro bioactivity of containing bioactive glasses and glass-ceramics, J Biomater APPL

23. Ni S, Chang J, Chou L, Zhai W. Comparison of osteoblast-like cell responses to silicate and tricalcium 磷酸盐 ceramics in vitro. J Biomed Mater Res B

24. Xie Y, Zheng X, Ding C, Zhai W, Chang J, and Ji H. Preparation and Characterization of CaO-ZrO2-SiO2 Coating for Potential Application in Biomedicine. J Thermal Spray Technol

25. Zhao W, Chang J, Wang J, Zhai W and Wang Z. In vitro bioactivity of novel tricalcium silicate ceramics. Journal of Materials Science: Materials in Medicine

26. Wang KW, Zhu YJ, Chen XY, Zhai W, Wang Q, Chen F, Chang J and Duan Y-R. Flower-like hierarchically nanostructured hydroxyapatite hollow spheres: facile preparation and application in anticancer drug cellular delivery. Chemistry – An Asian Journal

27. Ning C, Ding D, Dai K, Zhai W and Chen L. The effect of Zr content on the microstructure, mechanical properties and cell attachment of 德州仪器35Nb–xZr alloys. Biomed. Mater

28. Chen F, Tang QL, Zhu YJ, Wang KW, Zhang ML, Zhai W, Chang J. 羟基磷灰石 nanorods/poly(vinyl pyrolidone) composite nanofibers, arrays and three-dimensional fabrics: Electrospun preparation and transformation to hydroxyapatite nanostructures. Acta Biomaterialia

29. Wanyin Zhai, Kaili Lin, Jiang Chang. Study on crosslinking of porcine heart 维尔福集团 matrix using procyanidins. The 8th Annual Meeting of Tissue Engineering Society Internation

30. 翟万银,常 江,赵 强,徐德明。组织工程心脏瓣膜病研究进展,国外医学。生物医学工程学

31. 翟万银,朱振勤,陈季武,王云丹,赵子寅,胡天喜。雷震子护康胶囊制剂抗氧化和对脱氧核糖核酸损伤保护作用研究,发光学报

32. 朱振勤,翟万银,陈季武,夏晶,傅蓓蓓,谢萍,胡天喜。葡萄籽提取物抗氧化及对DNA保护作用研究,华东师范大学学报

33. Zhu ZQ, Zhai WY, Chen JW, Xia J, Xie P. Effects of grape seed procyanidin scavenging free radicals and protecting cultured bovine aortic cells from oxidative damage. Acta biochemica et biophysica sinica

34. Lin KL, Zhai WY, Ni SY, Chang J, Zeng Y, Qian W, Study of the mechanical property and in vitro biocompatibility of casio3 ceramics, Ceramics Inter松下电器

35. Wenyuan Zhao, Junying Wang, Wanyin Zhai, Zheng Wang, Jiang Chang. The self-setting properties and in vitro bioactivity of tricalcium silicate.Biomaterials

36. Wu CT, Chang J, Zhai WY, A novel hardystonite bioceramic: preparation and characteristics, Ceramics International

37. Gou Z, Chang J, Zhai W, Preparation and characterization of novel bioactive dicalcium silicate ceramics. J. Eur. Ceram. Soc

38. Zhao L, Chang J, Zhai W. Effect of dissolution and different crystallographic phasephases of TiO2 on hepatocyte response in vitro. Journal of Biomaterials Applications

39. Gou Z, Chang J, Zhai W, Wang JY, Study on the self-setting property and the in vitro bioactivity of b-ca(clo)2SiO4, Journal of Biomedical Materials Research Part B (JBMR:B), Applied Biomaterials

40. Wu CT, Chang J, Wang JY, Ni SY, Zhai WY, Preparation and Characteristics of a Silicate (Bredigite) Bioactive Ceramic. Biomaterials

专利

(1)常江,翟万银. 发明名称“具有生物活性的人工生物瓣瓣膜的制备方法”.中国专利奖

(2)常江,翟万银. 发明名称“采用槲皮素交联制备人工生物心脏瓣膜病材料的方法”.中国专利申请号

(3)常江,翟万银. 发明名称“一种可再细胞化的人工生物心脏瓣膜”.中国专利申请号

参考资料

翟万银.中国科学院上海硅酸盐研究所.2012-12-10