Palbociclib
Palbociclib (PD-0332991) is an orally available pyrido嘧啶derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. Palbociclib is a highly specific inhibitor of cyclindependent kinase 4 (Cdk4) (IC50, 0.011 μmol/L) and Cdk6 (IC50, 0.016 μmol/L), having no activity against a panel of 36 additional protein kinases.
化学信息
外观：黄色至灰白色晶状固体
分子量 : 447.53
分子式: C24H29N7O2
CAS号: 571190-30-2
晶型：2种，A和B，均为无水晶体
储存条件: 参考CoA中推荐的条件进行储存。
临床信息
参考资料
medchemexpress.medchemexpress.cn.2015-04-27