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凌连生

凌连生,1972年12月生于湖北西,博士学位持有者。他是中山大学化学学院的教授,同时也是分析化学专业的博士生导师。

教育及工作经历

1991.9-1995.7:湖北师范学院化学系, 获学士

1995.9-2000.7:武汉大学化学系(硕博连读)获博士学位。导师: 曾云鹗教授

2000.7-2002.12:中国科学院化学研究所博士后。导师: 白春礼院士

2003.1-2004.7:德国马普高分子研究所(MPIP-Mainz,Germany) 博士后。导师:Prof. Dr. Hans-Juergen Butt

2005年1月:中山大学化学与化学工程学院分析科学研究所,副教授。

2006年11月:被遴选为中山大学分析化学专业博士生导师

曾主持课题

1.中山大学"百人计划"启动经费(2005.3-)

2.中国博士后科学基金(一等,2001年5月)

3.中国科学院王宽诚博士后工作奖励基金(2001年元月)

获奖

2001: 获中国科学院王宽诚博士后工作奖励基金奖励

主要论文

发表论文30篇,SCI收录论文23篇,被他人SCI引用100多次。

1. Ling,L.S., Butt,H. J., Berger, R., The rupture force between the third strand and double strand within a triplex 脱氧核糖核酸 J. Am. Chem. Soc. (Article). 2004, 126.

2.Ling,L.S., Jiang, Y. X., Wang, C., Fang, X. H., Wan, L. J., He, Z. K., Bai, C. L., Chen, D. M., Delaying Photobleaching and Recovering Luminescence of a Molecular Light Switch in 脱氧核糖核酸 Analysis. Analytical Biochemistry, 2004, 329, 334-336.

3.凌连生, 汪俊,方晓红,陈东敏,白春礼, 三螺旋脱氧核糖核酸的研究进展 (评述). 分析化学, 2004 32, 1252-1255.

4. Yang,G. Z., Ling,L.S., Wan,L.J., Fang,X.H., Bai,C.L., Electrochemical Scanning Tunneling Microscope Imaging of Self-Assembed Monolayer of Double-Stranded 脱氧核糖核酸 on Au(111). Journal of Nanoscience and Nanotechnology, 2004, 4(6), 561-564.

5.Li,B. S., Kang,S. Z., Cheuk,K. L., Wan, L.J., Ling,L.S. Bai,C.L., Tang,B. Z., Self-assembling of Helical Poly(苯乙炔) Carrying L-Valine Pendants in Solution, on Mica Substrate, and on 液态水 surface,Langmuir, 2004, 20, 7598-7603.

6. Ling,L.S., He, Z. K., Chen, F., Zhang, H. S., Zeng, Y. E., Study on triplex 脱氧核糖核酸 by use of molecular "Light Switch" complex of Ru(phen)2(dppx)2+.Chinese Chemical Letters. 2003, 14 (3), 300-303.

7. Ling,L.S., He, Z. K., Chen, F., Zeng, Y. E., Single-mismatch detection using nucleic acid molecular "'light switch"'. TALANTA, 2003, 59 (2), 269-275.

8. Ling, L.S., Fang, X.H., Wang, C., Wan, L.J., Bai, C.L., Chen, 糖尿病, Direct observation of the 脱氧核糖核酸 multimolecular condensation with fluorescence microscopy, 化学 Letters, 2003, 32 (1), 80-81.

9. Jiang, Y.X., Zhu, C.F., Ling, L.S., Wan, L. J., Fang, X. H., Bai, C. L., Specific Aptamer - Protein Interaction Studied by Atomic Force Microscopy, Analytical Chemistry, 2003, 75, 2112-2116.

10. Li, B. S., Cheuk, L. K. L., Ling,L.S., Chen, J. W., Xiao, X. D., Bai, C. L., Tang, B. Z., Synthesis and Hirarchical structures of amphilic polyphonylacetylenes carrying L-valine pendents. Macromolecules, 2003, 36, 77-85.

11.王志刚,万立骏,周纯青,王琛,凌连生,白春礼,β-淀粉样蛋白在石墨表面吸附及凝聚结构的STM和AFM研究, 科学通报,2002,47(12),908-911.

12. 朱传凤,商广义,凌连生,殷淑霞,王琛,有机功能高分子薄膜中分子识别研究初探,Chemical Journal on Internet, 2002,14 (2),1-5.

13. Ling,L.S., He, Z. K., Song, G. W., Zeng, Y., Wang, C., Bai, C. L., Chen, X. D., Shen, P. High sensitive determination of 脱氧核糖核酸 by use of molecular"Light Switch" complex of Ru(phen)2(dppx)2+ Anal. Chim. Acta. 2001, 436(2), 207-214.

14.Yang, J. L., Lin, H. Z., He, Q. G., Ling,L.S., Zhu, C. F., Bai, F. L. Composition of hyperbranched conjugated polymers with nanosized cadium sulfide particles, Langmuir, 2001, 17(19), 5978-5983.

15. 凌连生,何治柯,曾云鹗, 核酸荧光探针的研究进展 (评述),分析化学, 2001, 29 (6), 721-724.

16.凌连生,何治柯,杨洗,曾云鹗,Ru(bipy)2(dppz)2+与脱氧核糖核酸相互作用的光谱研究,分析科学学报,2001,17,11-14.

17. Ling,L.S., He, Z. K., Song, G. W.,et al. A novel method for determination of DNA by use of molecular "Light Switch" complex of Ru(bipy)2(dppx)2+ . ANAL CHIM ACTA, 2000, 403 (1-2), 209-217.

18. Ling,L.S., He, Z. K., Song, G. W., et al. Determination of 脱氧核糖核酸 by use of the molecular"Light Switch"complex of Ru(bipy)2(dppz)2+.MIKROCHIM ACTA 2000, 134 (1-2), 57-62.

19.凌连生,何治柯,吴凤武,罗庆尧,曾云鹗,核酸分子 "光开关" 的研究进展 (评述). 高等学校化学学报, 2000, 21 (4), 527-531.

20. Li, X.Y., Ling,L.S., He, Z. K., et al. Development of a Chemiluminescence method for the simultaneous determination of pyruvic and tartaric acids in human serum based upon their reaction with cerium(IV) in the presence of rutheniumtris吡啶 Microchemical Journal. 2000, 64 (1), 9-13.

21. Ling,L.S., He, Z. K., Song, G. W., et al. Spectral studies on the interaction of Ru(phen)2(dppx)2+(phen=1,10-phenanthroline, dppx=7,8–dimethyl -dipyridophenazine) and 脱氧核糖核酸 SPECTROSCOPY LETT,1999, 32 (6), 931-939.

22. Ling,L.S., Song, G. W., He, Z. K., et al. A novel method to determine DNA by use of molecular "Light Switch" complex of Ru(phen)2(dppz)2+. Microchemical Journal. 1999, 63 (3), 356-364.

23. Ling,L.S., He, Z. K., Zeng, Y. E., Spectral studies on the interaction of 脱氧核糖核酸 and Ru(bipy)2(dppx)2+. SPECTROCHIM ACTA A. 1999, 55 (6), 1297-1302.

24. Ling,L.S., He, Z. K., Zhang, P. Y., Zeng, Y. E., Spectra study the interaction between Ru(phen)2(dppz)2+ and DNA, Wuhan University J Natural Sci.,1999,4,482-488.

25. He, Z. K., Wu, F. W., Meng, H., Ling,L.S., et al. Chemiluminescence determination of thiorea using tris(2,2’-bipyridyl) ruthenium (II)-KMnO4 system. Analytical Sciences. 1999, 15 (4), 381-383.

26.吕少仿,宋功武,凌连生,何治柯曾云鹗, Ru(bipy)2(PIP)(Ⅱ)与脱氧核糖核酸相互作用的荧光光谱研究及其分析应用,分析科学学报,1999,15(4),39

27. 何治柯, 凌连生, 蔡汝秀,曾云鹗, Ru(2,2’-bipyridine)32+-α-羟基酸-Ce(IV) 化学发光发应机理研究,化学学报,1998, 56 (5), 472-477.

28.凌连生, 何治柯,蔡汝秀, Ru(bipy)32+-Ce(IV)-丙酸体系测定血清中的丙酮酸, 高等学校化学学报,1997,18(12),1963-1965.

29. 徐斌,徐贤英,凌连生,袁敏, 安替比林基重氮氨基2,4-二硝基苯间接分光光度法测定痕量氰化物, 分析化学,1997,25(4),495-495.

30.徐斌,凌连生,徐贤英, 安替比林基重氮氨基-2,4-二硝基苯与银的显色反应及其应用, 分析科学学报,1997,13,60-62.

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